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Reference

Prescription medications

A reference for 25 prescription medications used in longevity, metabolic, and skin/hair care. Open any card to see the dosage forms a pharmacy stocks and whether they're available in the US and Canada.

Prescription-only โ€” not sold or addable here.

These are real medications dispensed only by a licensed pharmacy with a valid prescription. This page is educational reference, not medical advice, a recommendation, or an offer to sell. Talk to a licensed physician about any medication.

Tretinoin
Topical ยท skin
PrescriptionStrong evidence

Note: Tretinoin is a prescription drug, not a dietary supplement or cosmetic. It is prescribed by a clinician and used under medical supervision. (No structure/function supplement claim applies.)

0.01โ€“0.1 %

Prescription in US

PrescriptionModerate evidence

Prescription mTOR-inhibitor drug; this is a regulated medication, not a dietary supplement, and any therapeutic use is governed by its approved drug labeling and a prescribing clinician rather than a structure/function supplement claim.

0.5โ€“6 mg

Prescription in US

PrescriptionStrong evidence

Prescription biguanide antidiabetic drug; this is a regulated medication, not a dietary supplement, and any therapeutic use is governed by its approved drug labeling and a prescribing clinician rather than a structure/function supplement claim.

500โ€“2,550 mg

Prescription in US

PrescriptionPreliminary

Prescription opioid-antagonist drug used off-label at low doses; this is a regulated drug, not a dietary supplement, and any therapeutic effects are governed by clinical evidence and prescriber judgement rather than a structure/function supplement claim.

1.5โ€“4.5 mg

Not available in US

PrescriptionStrong evidence

Prescription oral retinoid for severe acne; this is a regulated drug, not a dietary supplement, and its indications and risk-management requirements are governed by its approved drug labeling rather than a structure/function supplement claim.

20โ€“80 mg

Prescription in US

Topical ยท skin
PrescriptionStrong evidence

Note: Trifarotene (Aklief) is a prescription topical drug (a fourth-generation retinoid), not a dietary supplement or cosmetic. It is prescribed by a clinician and used as labeled for acne; its indications are governed by its approved drug labeling rather than a structure/function supplement claim.

0 %

Prescription in US

PrescriptionStrong evidence

Prescription-only drug for men; this is a regulated drug, not a dietary supplement, and any therapeutic indications are governed by its approved drug labeling rather than a structure/function supplement claim.

0.5 mg

Prescription in US

PrescriptionModerate evidence

Prescription drug; this is a regulated medication, not a dietary supplement. Oral use for hair loss is off-label and any indications are governed by drug labeling and prescriber judgment rather than a structure/function supplement claim.

0.25โ€“40 mg

Prescription in US

PrescriptionStrong evidence

Prescription-only aldosterone-antagonist drug; this is a regulated drug, not a dietary supplement, and any therapeutic indications are governed by its approved drug labeling rather than a structure/function supplement claim.

25โ€“200 mg

Prescription in US

PrescriptionStrong evidence

Prescription-only, controlled-substance hormone replacement drug for men with diagnosed hypogonadism; this is a regulated drug, not a dietary supplement, and any therapeutic indications are governed by its approved drug labeling rather than a structure/function supplement claim.

50โ€“400 mg

Prescription in US

PrescriptionStrong evidence

Prescription-only thyroid hormone replacement drug; therapeutic uses are governed by its approved drug labeling rather than a structure/function supplement claim. Educational reference only.

25โ€“200 mcg

Prescription in US

PrescriptionStrong evidence

Prescription-only thyroid hormone (T3) drug; therapeutic uses are governed by its approved drug labeling rather than a structure/function supplement claim. Educational reference only.

5โ€“75 mcg

Prescription in US

PrescriptionStrong evidence

Estradiol is the body's primary estrogen and plays a central role in female reproductive physiology, bone density maintenance, and menopausal symptom regulation. Educational reference only.

0.5โ€“2 mg

Prescription in US

PrescriptionStrong evidence

Progesterone is the principal endogenous progestogen and is central to the menstrual cycle, endometrial balance, and pregnancy maintenance. Educational reference only.

100โ€“300 mg

Prescription in US

PrescriptionStrong evidence

Prescription-only PDE5-inhibitor drug; this is a regulated medication, not a dietary supplement, and its uses are governed by approved drug labeling rather than a structure/function supplement claim.

2.5โ€“5 mg

Prescription in US

PrescriptionStrong evidence

Prescription-only alpha-glucosidase-inhibitor drug; this is a regulated medication, not a dietary supplement, and its uses are governed by approved drug labeling rather than a structure/function supplement claim.

25โ€“100 mg

Prescription in US

PrescriptionStrong evidence

Prescription-only drug; this is a regulated medication, not a dietary supplement, and any therapeutic indications are governed by its approved drug labeling rather than a structure/function supplement claim.

10โ€“25 mg

Prescription in US

PrescriptionStrong evidence

Prescription-only drug; this is a regulated medication, not a dietary supplement, and any therapeutic indications are governed by its approved drug labeling rather than a structure/function supplement claim.

20โ€“80 mg

Prescription in US

Injectable
PeptideStrong evidence

Prescription-only drug; this is a regulated medication, not a dietary supplement, and any indications are governed by its approved drug labeling rather than a structure/function supplement claim.

2.5โ€“15 mg

Prescription in US

Injectable
PeptideStrong evidence

Prescription incretin (GLP-1 receptor agonist) drug; this is a regulated pharmaceutical, not a dietary supplement, and its uses are governed by approved drug labeling rather than any structure/function supplement claim.

0.25โ€“2.4 mg

Prescription in US

Injectable
PeptideStrong evidence

Prescription incretin (GLP-1 receptor agonist) drug; this is a regulated pharmaceutical, not a dietary supplement, and its uses are governed by approved drug labeling rather than any structure/function supplement claim.

0.6โ€“3 mg

Prescription in US

Injectable
PeptideModerate evidence

A melanocortin (MC4R) receptor agonist peptide used under medical supervision and administered by subcutaneous injection. (Prescription peptide drug; not a dietary supplement.)

1.8 mg

Prescription in US

Injectable
PeptideModerate evidence

A gonadotropin-releasing hormone (GnRH) analogue studied for its role in stimulating the pituitary's release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). (Prescription drug; not a dietary supplement; no disease claims.)

mcg

Prescription in US

PrescriptionLimited / mixed

Investigational triple monoamine reuptake inhibitor studied for appetite regulation and reduced energy intake; not established or approved for any human use and not a lawful supplement.

mg

Not available in US

Oral care
DentalStrong evidence

A prescription antiseptic oral rinse used under professional direction to help reduce dental plaque and support gum cleanliness; this is a regulated drug, not a dietary supplement, and its indications are governed by its approved drug labeling rather than a structure/function supplement claim.

0.12โ€“0.2 %

Prescription in US